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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC1
All Species:
25.45
Human Site:
S78
Identified Species:
50.91
UniProt:
Q8IUR5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUR5
NP_787057.2
774
87338
S78
A
F
L
S
Y
N
R
S
L
D
Q
G
C
V
G
Chimpanzee
Pan troglodytes
XP_520818
882
98885
S186
A
F
L
S
Y
N
R
S
L
D
Q
G
C
V
G
Rhesus Macaque
Macaca mulatta
XP_001101625
1044
115045
S348
A
F
L
S
Y
N
R
S
L
D
Q
G
C
V
G
Dog
Lupus familis
XP_543747
865
97589
S169
A
F
L
S
Y
N
R
S
V
D
Q
H
H
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV71
942
105796
S185
A
F
L
S
Y
Q
R
S
L
D
Q
G
C
A
G
Rat
Rattus norvegicus
XP_342789
942
106226
S185
A
F
L
S
Y
H
R
S
L
D
Q
D
C
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416374
944
106377
S192
A
F
L
S
Y
N
R
S
V
D
Q
L
Y
V
G
Frog
Xenopus laevis
Q6DCD5
836
94386
L153
L
F
F
L
L
S
L
L
C
Y
M
K
H
C
S
Zebra Danio
Brachydanio rerio
XP_001922025
866
97506
F183
S
M
L
F
L
L
A
F
L
S
Y
I
R
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
Y208
F
L
A
A
F
L
S
Y
A
K
S
V
G
D
S
Honey Bee
Apis mellifera
XP_393964
996
112258
A156
S
S
L
F
Y
L
A
A
L
I
T
Y
T
K
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788690
569
64719
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
73.1
83.6
N.A.
73
72.8
N.A.
N.A.
66.3
23.3
52.4
N.A.
26.8
24.1
N.A.
33.4
Protein Similarity:
100
87.4
73.4
86.2
N.A.
78
78
N.A.
N.A.
72.9
41
66.1
N.A.
44.1
39.5
N.A.
48
P-Site Identity:
100
100
100
80
N.A.
86.6
80
N.A.
N.A.
80
6.6
13.3
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
13.3
20
N.A.
13.3
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
9
9
0
0
17
9
9
0
0
0
0
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
42
9
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
59
0
9
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
67
9
17
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
34
9
0
59
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
9
17
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
9
0
9
0
% K
% Leu:
9
9
75
9
17
25
9
9
59
0
0
9
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
59
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
59
0
0
0
0
0
9
0
0
% R
% Ser:
17
9
0
59
0
9
9
59
0
9
9
0
0
9
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
17
0
0
9
0
42
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
67
0
0
9
0
9
9
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _